SCHEMBL30933712

SCHEMBL30933712

CCCOc1ccc(Cl)cc1CNC[C@@H]1CCNC1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.50
PKM P14618 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
CYP1A2 P05177 2/20 0.44
CYP2D6 P10635 2/20 0.44
KDM4E B2RXH2 1/20 0.42
HIF1A Q16665 1/20 0.42
PRMT5 O14744 1/20 0.39
WDR77 Q9BQA1 1/20 0.39
CMA1 P23946 1/20 0.39
HTR2C P28335 3/20 0.38
HTR2B P41595 3/20 0.38
ATM Q13315 1/20 0.38
KCNT1 Q5JUK3 1/20 0.37
SLC6A2 P23975 1/20 0.37
SLC6A4 P31645 1/20 0.37
RAB9A P51151 1/20 0.36
NLRP3 Q96P20 2/20 0.36
F10 P00742 1/20 0.36
CCR5 P51681 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL30933786 0.99 MAPT (0.49) MAPTPKML3MBTL1CYP1A2CYP2D6
SCHEMBL30933772 0.93 MAPT (0.52) MAPTPKML3MBTL1CYP1A2CYP2D6
Hydrochloric Acid SCHEMBL30933681 0.92 MAPT (0.51) MAPTPKML3MBTL1CYP1A2CYP2D6
SCHEMBL30933700 0.91 CYP1A2 (0.54) MAPTPKML3MBTL1CYP1A2CYP2D6
SCHEMBL30933789 0.91 CYP1A2 (0.54) MAPTPKML3MBTL1CYP1A2CYP2D6
Hydrochloric Acid SCHEMBL30933732 0.90 CYP1A2 (0.56) MAPTPKML3MBTL1CYP1A2CYP2D6
Hydrochloric Acid SCHEMBL30933678 0.90 CYP1A2 (0.56) MAPTPKML3MBTL1CYP1A2CYP2D6
Hydrochloric Acid SCHEMBL30933661 0.85 SLC6A4 (0.44) CYP1A2CYP2D6PRMT5WDR77HTR2C
SCHEMBL30933715 0.84 PRMT5 (0.46) MAPTPKML3MBTL1CYP2D6PRMT5
SCHEMBL30933773 0.84 CYP2D6 (0.56) MAPTPKML3MBTL1CYP1A2CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024105007-A1 AUTOPHAGY INDUCING COMPOUNDS AND USES THEREOF Samsara Therapeutics Inc. (US) 2024-05-23 WO disclosed