Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.46 |
| ▸ | MAPK8 | P45983 | 3/20 | 0.45 |
| ▸ | STS | P08842 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.42 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.42 |
| ▸ | FNTA | P49354 | 1/20 | 0.42 |
| ▸ | FNTB | P49356 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30933838 | 0.87 | KDM4E (0.48) | KDM4EPKMGPR119MAPK8STS | |
| SCHEMBL30933710 | 0.86 | KDM4E (0.48) | KDM4EPKMGPR119MAPK8STS | |
| SCHEMBL30933770 | 0.86 | KDM4E (0.47) | KDM4EPKMGPR119MAPK8STS | |
| SCHEMBL30933771 | 0.86 | PKM (0.47) | KDM4EPKMGPR119MAPK8STS | |
| SCHEMBL30933722 | 0.85 | KDM4E (0.53) | KDM4EPKMMAPK8STSTGFBR1 | |
| SCHEMBL30933821 | 0.85 | KDM4E (0.46) | KDM4EPKMGPR119MAPK8STS | |
| SCHEMBL30933753 | 0.85 | KDM4E (0.48) | KDM4EPKMGPR119MAPK8STS | |
| SCHEMBL30933702 | 0.84 | KDM4E (0.48) | KDM4EPKMGPR119MAPK8STS | |
| SCHEMBL30933798 | 0.83 | FNTA (0.48) | KDM4EPKMGPR119MAPK8STS | |
| SCHEMBL30933793 | 0.82 | KDM4E (0.48) | KDM4EPKMGPR119MAPK8STS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024105007-A1 | AUTOPHAGY INDUCING COMPOUNDS AND USES THEREOF | Samsara Therapeutics Inc. (US) | 2024-05-23 | — | — | WO | disclosed |