Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH2 | P25021 | 7/20 | 0.50 |
| ▸ | HRH1 | P35367 | 7/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30933800 | 0.80 | CYP1A2 (0.60) | CYP2D6CYP1A2ATMLMNATP53 | |
| SCHEMBL30933717 | 0.79 | CYP2D6 (0.59) | CYP2D6CYP1A2ATMTSHRLMNA | |
| Hydrochloric Acid SCHEMBL30933668 | 0.78 | CYP2D6 (0.61) | CYP2D6CYP1A2ATMTSHRLMNA | |
| SCHEMBL30933847 | 0.77 | CYP2D6 (0.57) | CYP2D6CYP1A2ATMTSHRLMNA | |
| Hydrochloric Acid SCHEMBL30933672 | 0.76 | CYP2D6 (0.59) | CYP2D6CYP1A2ATMTSHRLMNA | |
| SCHEMBL30933714 | 0.71 | L3MBTL1 (0.43) | CYP2D6CYP1A2ATMTSHRSMN1; SMN2 | |
| SCHEMBL30933726 | 0.70 | CYP1A2 (0.69) | CYP2D6CYP1A2ATMSMN1; SMN2LMNA | |
| Hydrochloric Acid SCHEMBL30933695 | 0.69 | CYP1A2 (0.71) | CYP2D6CYP1A2ATMSMN1; SMN2LMNA | |
| SCHEMBL30902413 | 0.69 | VEGFA (0.54) | TSHRSMN1; SMN2ALDH1A1KMT2AKDM4E | |
| Hydrochloric Acid SCHEMBL4377908 | 0.69 | HRH2 (0.71) | HRH2HRH1TSHRSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024105007-A1 | AUTOPHAGY INDUCING COMPOUNDS AND USES THEREOF | Samsara Therapeutics Inc. (US) | 2024-05-23 | — | — | WO | disclosed |