Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 2/20 | 0.38 |
| ▸ | HTR2B | P41595 | 2/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | DDR1 | Q08345 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30933703 | 0.94 | CYP1A2 (0.43) | CYP1A2CYP2D6PTGER1KMT2AL3MBTL1 | |
| SCHEMBL30933830 | 0.92 | MAPK8 (0.45) | CYP1A2CYP2D6PTGER1KMT2AL3MBTL1 | |
| SCHEMBL30933889 | 0.81 | ANO1 (0.45) | CYP1A2CYP2D6PTGER1KMT2ANPBWR1 | |
| SCHEMBL30933701 | 0.81 | MAPK8 (0.44) | PTGER1MAPK8HTR2CHTR2BDRD2 | |
| SCHEMBL29725626 | 0.79 | GAA (0.52) | CYP1A2KMT2AL3MBTL1POLBMEN1 | |
| SCHEMBL30933805 | 0.78 | AHCY (0.48) | CYP1A2CYP2D6L3MBTL1MAPK8 | |
| SCHEMBL30902410 | 0.78 | DDR1 (0.54) | KDM4DDRD2DRD4DDR1 | |
| SCHEMBL30933796 | 0.77 | CYP1A2 (0.50) | CYP1A2CYP2D6KMT2AL3MBTL1NPBWR1 | |
| SCHEMBL30933756 | 0.77 | CYP1A2 (0.54) | CYP1A2CYP2D6PTGER1KMT2AL3MBTL1 | |
| SCHEMBL29725596 | 0.77 | KMT2A (0.52) | KMT2AL3MBTL1MAPK8DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024105007-A1 | AUTOPHAGY INDUCING COMPOUNDS AND USES THEREOF | Samsara Therapeutics Inc. (US) | 2024-05-23 | — | — | WO | disclosed |