Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 6/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.40 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.40 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.39 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4209586 | 1.00 | ERN1 (0.47) | ERN1TDP1HPGDALDH1A1CYP1A2 | |
| SCHEMBL6097515 | 0.87 | ERN1 (0.51) | ERN1TDP1ALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL14785211 | 0.86 | ERN1 (0.44) | ERN1TDP1HPGDALDH1A1CYP1A2 | |
| SCHEMBL3936165 | 0.82 | TSHR (0.66) | ERN1HPGDALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL11870708 | 0.82 | ERN1 (0.41) | ERN1TDP1HPGDALDH1A1CYP1A2 | |
| SCHEMBL15332582 | 0.82 | TSHR (0.66) | ERN1HPGDALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL613846 | 0.82 | ERN1 (0.47) | ERN1TDP1HPGDALDH1A1TSHR | |
| SCHEMBL30480709 | 0.82 | ERN1 (0.47) | ERN1TDP1HPGDALDH1A1TSHR | |
| SCHEMBL16950496 | 0.82 | TSHR (0.41) | ERN1HPGDALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL340634 | 0.82 | MDM2 (0.40) | HPGDALDH1A1CYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024105007-A1 | AUTOPHAGY INDUCING COMPOUNDS AND USES THEREOF | Samsara Therapeutics Inc. (US) | 2024-05-23 | — | — | WO | disclosed |