SCHEMBL340634

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4209586	0.82	ERN1 (0.47)	MDM2CSNK2A1TSHRHTR2AHTR2C
	SCHEMBL16957482	0.82	LMNA (0.38)	TSHRHPGDCYP1A2CYP3A4CYP2D6
	SCHEMBL16950496	0.82	TSHR (0.41)	MDM2CSNK2A1TSHRHTR2AHTR2C
	SCHEMBL30933788	0.82	ERN1 (0.47)	MDM2CSNK2A1TSHRHTR2AHTR2C
	SCHEMBL21059495	0.81	TSHR (0.64)	TSHRHTR2AHTR2CHTR2BHPGD
	SCHEMBL21059493	0.81	TSHR (0.64)	TSHRHTR2AHTR2CHTR2BHPGD
	SCHEMBL6935704	0.80	ALDH1A1 (0.41)	MDM2SMN1; SMN2ALOX12GLABRD4
	SCHEMBL13257964	0.80	P2RX3 (0.39)	CSNK2A1TSHRHPGDSMN1; SMN2ALOX12
	SCHEMBL16957006	0.79	KDM4E (0.48)	TSHRHPGDSMN1; SMN2LMNAMEN1
	SCHEMBL11804961	0.79	TTR (0.42)	TSHRHPGDSMN1; SMN2CYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.