Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.55 |
| ▸ | IDO1 | P14902 | 2/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.40 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30933809 | 0.88 | CYP1A2 (0.56) | CYP1A2CYP2D6IDO1ATMALDH1A1 | |
| SCHEMBL30933756 | 0.81 | CYP1A2 (0.54) | CYP1A2CYP2D6IDO1ATMMEN1 | |
| SCHEMBL30933711 | 0.79 | CYP1A2 (0.62) | CYP1A2CYP2D6ATMKDM4EALDH1A1 | |
| SCHEMBL28962997 | 0.78 | IDO1 (0.53) | CYP1A2CYP2D6IDO1KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL30933707 | 0.78 | CYP1A2 (0.64) | CYP1A2CYP2D6ATMKDM4EALDH1A1 | |
| SCHEMBL13857331 | 0.78 | TAS1R3 (0.45) | ADRB2HTR1AKDM4E | |
| SCHEMBL7255220 | 0.78 | KDM4E (0.48) | IDO1KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL7254326 | 0.78 | KDM4E (0.48) | CYP1A2CYP2D6IDO1KDM4EALDH1A1 | |
| SCHEMBL30933800 | 0.77 | CYP1A2 (0.60) | CYP1A2CYP2D6ATMKDM4EALDH1A1 | |
| SCHEMBL18106068 | 0.76 | IDO1 (0.54) | CYP1A2CYP2D6IDO1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024105007-A1 | AUTOPHAGY INDUCING COMPOUNDS AND USES THEREOF | Samsara Therapeutics Inc. (US) | 2024-05-23 | — | — | WO | disclosed |