Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 5/20 | 0.70 |
| ▸ | NPC1 | O15118 | 4/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.70 |
| ▸ | RAB9A | P51151 | 2/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.70 |
| ▸ | MTOR | P42345 | 2/20 | 0.67 |
| ▸ | MEN1 | O00255 | 4/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.63 |
| ▸ | MAPT | P10636 | 3/20 | 0.63 |
| ▸ | DDX3X | O00571 | 2/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | HTT | P42858 | 1/20 | 0.63 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.63 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.57 |
| ▸ | ITGAV | P06756 | 1/20 | 0.57 |
| ▸ | BAZ1A | Q9NRL2 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25956566 | 1.00 | IRAK4 (0.70) | IRAK4NPC1SMN1; SMN2RAB9AALDH1A1 | |
| SCHEMBL30933737 | 0.87 | NPC1 (0.72) | IRAK4NPC1SMN1; SMN2RAB9AALDH1A1 | |
| SCHEMBL27093079 | 0.85 | RIPK1 (0.72) | IRAK4NPC1SMN1; SMN2RAB9AALDH1A1 | |
| SCHEMBL3597174 | 0.82 | IRAK4 (1.00) | IRAK4NPC1SMN1; SMN2RAB9AALDH1A1 | |
| SCHEMBL21858357 | 0.82 | IRAK4 (0.63) | IRAK4NPC1SMN1; SMN2RAB9AALDH1A1 | |
| SCHEMBL30933642 | 0.81 | MTOR (0.73) | NPC1SMN1; SMN2RAB9AALDH1A1MTOR | |
| SCHEMBL11423733 | 0.81 | MTOR (0.73) | NPC1SMN1; SMN2RAB9AALDH1A1MTOR | |
| SCHEMBL30933646 | 0.81 | MTOR (0.73) | NPC1SMN1; SMN2RAB9AMTORMEN1 | |
| SCHEMBL30933641 | 0.81 | MTOR (0.73) | NPC1SMN1; SMN2RAB9AMTORMEN1 | |
| SCHEMBL30933648 | 0.81 | MTOR (0.73) | NPC1RAB9AALDH1A1MTORMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024128568-A1 | BENZIMIDAZOLYLUREA DERIVATIVE AND PHARMACEUTICAL USE THEREOF | 경북대학교 산학협력단 | 2024-06-20 | — | — | WO | disclosed |