Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 1/20 | 0.46 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.41 |
| ▸ | JAK1 | P23458 | 3/20 | 0.39 |
| ▸ | JAK3 | P52333 | 3/20 | 0.39 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.38 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.38 |
| ▸ | CDK2 | P24941 | 2/20 | 0.38 |
| ▸ | TYK2 | P29597 | 2/20 | 0.38 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.38 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL30933657 | 0.99 | PRMT5 (0.45) | PRMT5WDR77CHRM1JAK1JAK3 | |
| SCHEMBL30933867 | 0.90 | PRMT5 (0.53) | PRMT5WDR77CHRM1HTR4CHRM3 | |
| Hydrochloric Acid SCHEMBL30933675 | 0.89 | PRMT5 (0.52) | PRMT5WDR77CHRM1HTR4CHRM3 | |
| SCHEMBL30933773 | 0.81 | CYP2D6 (0.56) | PRMT5WDR77CHRM1CHRM3SLC2A1 | |
| SCHEMBL30933924 | 0.81 | PRMT5 (0.42) | PRMT5WDR77CYP2D6HTR2ASLC6A4 | |
| Hydrochloric Acid SCHEMBL30933664 | 0.80 | MAPK1 (0.44) | PRMT5WDR77CYP2D6ATMHTR2A | |
| Hydrochloric Acid SCHEMBL30933803 | 0.80 | CYP1A2 (0.58) | PRMT5WDR77CHRM1SLC2A1CYP2D6 | |
| Hydrochloric Acid SCHEMBL30933667 | 0.80 | PRMT5 (0.47) | PRMT5WDR77CHRM1CHRM3SLC2A1 | |
| SCHEMBL30933785 | 0.78 | PRMT5 (0.41) | PRMT5WDR77CHRM1CHRM3CHRM2 | |
| Hydrochloric Acid SCHEMBL30933659 | 0.77 | PRMT5 (0.40) | PRMT5WDR77SLC2A1HTR2ASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024105007-A1 | AUTOPHAGY INDUCING COMPOUNDS AND USES THEREOF | Samsara Therapeutics Inc. (US) | 2024-05-23 | — | — | WO | disclosed |