Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 1/20 | 0.53 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.53 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | EP300 | Q09472 | 4/20 | 0.38 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.37 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.37 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL30933675 | 0.99 | PRMT5 (0.52) | PRMT5WDR77HTR4CYP2D6MEN1 | |
| SCHEMBL30933875 | 0.90 | PRMT5 (0.46) | PRMT5WDR77HTR4CYP2D6MEN1 | |
| Hydrochloric Acid SCHEMBL30933657 | 0.89 | PRMT5 (0.45) | PRMT5WDR77HTR4CYP2D6MEN1 | |
| SCHEMBL30933773 | 0.85 | CYP2D6 (0.56) | PRMT5WDR77CYP2D6MEN1TP53 | |
| Hydrochloric Acid SCHEMBL30933667 | 0.84 | PRMT5 (0.47) | PRMT5WDR77CYP2D6MEN1TP53 | |
| Hydrochloric Acid SCHEMBL30933803 | 0.84 | CYP1A2 (0.58) | PRMT5WDR77CYP2D6MEN1TP53 | |
| SCHEMBL30933924 | 0.80 | PRMT5 (0.42) | PRMT5WDR77CYP2D6CYP1A2SLC6A2 | |
| Hydrochloric Acid SCHEMBL30933745 | 0.79 | PRMT5 (0.67) | PRMT5WDR77MEN1KMT2ASLC2A1 | |
| Hydrochloric Acid SCHEMBL30933664 | 0.79 | MAPK1 (0.44) | PRMT5WDR77CYP2D6CYP1A2SLC6A2 | |
| SCHEMBL30933765 | 0.79 | EP300 (0.49) | PRMT5WDR77HTR4CYP2D6CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024105007-A1 | AUTOPHAGY INDUCING COMPOUNDS AND USES THEREOF | Samsara Therapeutics Inc. (US) | 2024-05-23 | — | — | WO | disclosed |