Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 4/20 | 0.48 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | TDO2 | P48775 | 1/20 | 0.43 |
| ▸ | KIF11 | P52732 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | TOP2A | P11388 | 1/20 | 0.40 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.39 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25025764 | 1.00 | SNCA (0.48) | SNCASTING1CYP2C9LMNAHPGD | |
| SCHEMBL25025556 | 0.88 | STING1 (0.46) | SNCASTING1CYP2C9IDO1TDO2 | |
| SCHEMBL30233599 | 0.87 | STING1 (0.46) | SNCASTING1CYP2C9LMNAIDO1 | |
| SCHEMBL25025629 | 0.87 | STING1 (0.46) | SNCASTING1CYP2C9LMNAIDO1 | |
| SCHEMBL25025720 | 0.87 | STING1 (0.46) | SNCASTING1CYP2C9LMNAIDO1 | |
| SCHEMBL25025585 | 0.86 | STING1 (0.47) | SNCASTING1CYP2C9LMNAIDO1 | |
| SCHEMBL25026130 | 0.85 | MAOB (0.51) | STING1CYP2C9CYP1A2CYP2C19TRPV1 | |
| SCHEMBL25025752 | 0.85 | STING1 (0.47) | SNCASTING1CYP2C9LMNAIDO1 | |
| SCHEMBL25554406 | 0.85 | LMNA (0.52) | SNCASTING1CYP2C9LMNAHPGD | |
| SCHEMBL25025753 | 0.85 | STING1 (0.46) | SNCASTING1CYP2C9LMNAIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118119595-A | Compounds and compositions for the treatment of diseases associated with STING activity | 艾福姆德尤股份有限公司 | 2024-05-31 | — | — | CN | disclosed |