Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 12/20 | 0.40 |
| ▸ | LIPG | Q9Y5X9 | 12/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 4/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10158676 | 1.00 | LPL (0.40) | LPLLIPGROCK1BACE1P2RX7 | |
| SCHEMBL31394725 | 0.91 | LPL (0.41) | LPLLIPGROCK1BACE1CA1 | |
| SCHEMBL10158552 | 0.90 | LPL (0.41) | LPLLIPGROCK1BACE1P2RX7 | |
| SCHEMBL2010946 | 0.85 | LPL (0.39) | LPLLIPGROCK1BACE1P2RX7 | |
| SCHEMBL24275634 | 0.81 | LPL (0.41) | LPLLIPGROCK1BACE1P2RX7 | |
| SCHEMBL31394797 | 0.81 | LPL (0.42) | LPLLIPGROCK1BACE1CA1 | |
| SCHEMBL5781980 | 0.80 | LPL (0.46) | LPLLIPGBACE1P2RX7CA1 | |
| SCHEMBL4158988 | 0.80 | LPL (0.44) | LPLLIPGROCK1BACE1P2RX7 | |
| SCHEMBL30284869 | 0.80 | LPL (0.44) | LPLLIPGROCK1BACE1P2RX7 | |
| SCHEMBL2011756 | 0.79 | LPL (0.41) | LPLLIPGROCK1BACE1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024125464-A1 | TETRAHYDROISOQUINOLIN-ONE DERIVATIVES, PREPARATION METHODS AND MEDICINAL USES THEREOF | JIANGSU HANSOH PHARMACEUTICAL GROUP CO., LTD. (CN) | 2024-06-20 | — | — | WO | disclosed |