Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 3/20 | 0.45 |
| ▸ | PARP1 | P09874 | 2/20 | 0.45 |
| ▸ | TDP2 | O95551 | 3/20 | 0.42 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.42 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
| ▸ | TGM2 | P21980 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | CMA1 | P23946 | 1/20 | 0.34 |
| ▸ | AHR | P35869 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 2/20 | 0.34 |
| ▸ | METAP1 | P53582 | 1/20 | 0.33 |
| ▸ | S100A4 | P26447 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24510107 | 0.88 | PARP10 (0.49) | PARP10PARP1TDP2PARP11AKR1A1 | |
| SCHEMBL12077241 | 0.84 | TDP2 (0.46) | PARP10PARP1TDP2PARP11AKR1A1 | |
| SCHEMBL24457320 | 0.82 | TDP2 (0.44) | PARP10PARP1TDP2PARP11AKR1A1 | |
| SCHEMBL24457118 | 0.82 | TDP2 (0.44) | PARP10PARP1TDP2PARP11AKR1A1 | |
| SCHEMBL23277636 | 0.81 | TDP2 (0.46) | PARP10PARP1TDP2PARP11AKR1A1 | |
| SCHEMBL24457294 | 0.81 | TDP2 (0.43) | PARP10PARP1TDP2PARP11AKR1A1 | |
| SCHEMBL24457643 | 0.81 | TDP2 (0.43) | PARP10PARP1TDP2PARP11AKR1A1 | |
| SCHEMBL12078131 | 0.75 | TDP2 (0.46) | PARP10PARP1TDP2PARP11AKR1A1 | |
| SCHEMBL24895277 | 0.75 | TDP2 (0.46) | PARP10PARP1TDP2PARP11AKR1A1 | |
| SCHEMBL30935124 | 0.74 | BACE1 (0.36) | BACE1CA1CA2CA4CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024125464-A1 | TETRAHYDROISOQUINOLIN-ONE DERIVATIVES, PREPARATION METHODS AND MEDICINAL USES THEREOF | JIANGSU HANSOH PHARMACEUTICAL GROUP CO., LTD. (CN) | 2024-06-20 | — | — | WO | disclosed |