Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29853707 | 1.00 | PDK2 (0.49) | PDK2NPC1ALDH1A1PLA2G1BNFKB1 | |
| SCHEMBL16596687 | 1.00 | PDK2 (0.49) | PDK2NPC1ALDH1A1PLA2G1BNFKB1 | |
| SCHEMBL20279810 | 0.92 | PDK2 (0.41) | PDK2NPC1RAB9AOPRD1MAPK14 | |
| SCHEMBL14681502 | 0.91 | PDK2 (0.43) | PDK2NPC1ALDH1A1PLA2G1BNFKB1 | |
| SCHEMBL30056023 | 0.91 | PDK2 (0.43) | PDK2NPC1ALDH1A1PLA2G1BNFKB1 | |
| SCHEMBL20196495 | 0.89 | PDK2 (0.47) | PDK2NPC1ALDH1A1PLA2G1BNFKB1 | |
| SCHEMBL26411258 | 0.89 | PDK2 (0.50) | PDK2ALDH1A1L3MBTL1MAPK14MEN1 | |
| SCHEMBL29706077 | 0.89 | PDK2 (0.47) | PDK2NPC1ALDH1A1PLA2G1BNFKB1 | |
| SCHEMBL24969208 | 0.88 | PDK2 (0.49) | PDK2NPC1ALDH1A1PLA2G1BNFKB1 | |
| SCHEMBL22870486 | 0.88 | PDK2 (0.44) | PDK2NPC1ALDH1A1PLA2G1BNFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112538046-B | Organic compound with aza-spiro-bifluorene structure and application thereof | 常州强力电子新材料股份有限公司 | 2024-06-07 | — | — | CN | disclosed |