SCHEMBL20196495

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL29706077	1.00	PDK2 (0.47)	PDK2KIF11STK10SLKKCNK18
	SCHEMBL16596687	0.89	PDK2 (0.49)	PDK2KIF11STK10SLKMAPK14
	SCHEMBL29853707	0.89	PDK2 (0.49)	PDK2KIF11STK10SLKMAPK14
	SCHEMBL30935419	0.89	PDK2 (0.49)	PDK2KIF11STK10SLKMAPK14
	SCHEMBL31584054	0.86	CNR1 (0.44)	PDK2KIF11STK10SLKKCNK18
	SCHEMBL24969208	0.86	PDK2 (0.49)	PDK2KIF11STK10SLKMAPK14
	SCHEMBL29462256	0.85	PDK2 (0.51)	PDK2MAPK14ALDH1A1L3MBTL1
	SCHEMBL12950969	0.85	PDK2 (0.51)	PDK2MAPK14ALDH1A1L3MBTL1
	SCHEMBL782290	0.85	PDK2 (0.51)	PDK2MAPK14ALDH1A1L3MBTL1
	SCHEMBL30359216	0.85	CNR1 (0.43)	PDK2KIF11STK10SLKKCNK18

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.