SCHEMBL30935533

SCHEMBL30935533

Cc1nc(-c2ccc(C)c(NC(=O)c3cnc4ccc(-c5cscn5)cn34)c2)no1

nearest known ligand 0.76

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
KIT P10721 20/20 0.76

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14741418 1.00 KIT (0.76) KIT
SCHEMBL30935626 0.90 KIT (0.62) KIT
SCHEMBL30935534 0.88 KIT (0.79) KIT
SCHEMBL14738526 0.86 KIT (1.00) KIT
SCHEMBL14741632 0.86 KIT (0.62) KIT
SCHEMBL30935497 0.86 KIT (0.68) KIT
SCHEMBL30935608 0.86 KIT (0.75) KIT
SCHEMBL14741787 0.86 KIT (0.58) KIT
SCHEMBL14741558 0.85 KIT (0.57) KIT
SCHEMBL14741646 0.84 KIT (0.60) KIT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4630424-A1 COMPOUNDS AND COMPOSITIONS AS C-KIT KINASE INHIBITORS Third Harmonic Bio, Inc. (US) 2025-10-15 EP disclosed
WO-2024124002-A1 COMPOUNDS AND COMPOSITIONS AS C-KIT KINASE INHIBITORS THIRD HARMONIC BIO, INC. (US) 2024-06-13 WO disclosed