SCHEMBL30935608

SCHEMBL30935608

Cc1nc(-c2ccc(C)c(NC(=O)c3cnc4ccc(-c5ccn(C)n5)cn34)c2)no1

nearest known ligand 0.75

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
KIT P10721 20/20 0.75

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30935584 0.90 KIT (0.62) KIT
SCHEMBL30935605 0.88 KIT (0.79) KIT
SCHEMBL14741688 0.87 KIT (0.76) KIT
SCHEMBL14741787 0.86 KIT (0.58) KIT
SCHEMBL14738634 0.86 KIT (1.00) KIT
SCHEMBL14741659 0.86 KIT (0.57) KIT
SCHEMBL14741560 0.86 KIT (0.58) KIT
SCHEMBL14741418 0.86 KIT (0.76) KIT
SCHEMBL30935533 0.86 KIT (0.76) KIT
SCHEMBL30935566 0.86 KIT (0.68) KIT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4630424-A1 COMPOUNDS AND COMPOSITIONS AS C-KIT KINASE INHIBITORS Third Harmonic Bio, Inc. (US) 2025-10-15 EP disclosed
WO-2024124002-A1 COMPOUNDS AND COMPOSITIONS AS C-KIT KINASE INHIBITORS THIRD HARMONIC BIO, INC. (US) 2024-06-13 WO disclosed