Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 2/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | FDPS | P14324 | 2/20 | 0.44 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.43 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.41 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.41 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10202643 | 0.86 | CHRM2 (0.48) | CHRM2CHRM1CHRM3CYP1A2HSD11B1 | |
| SCHEMBL30964068 | 0.84 | CHRNB2 (0.45) | CHRM2CHRM1CHRM3CYP1A2CYP3A4 | |
| SCHEMBL13609223 | 0.84 | CHRM2 (0.44) | CHRM2CHRM1CHRM3CYP1A2CYP3A4 | |
| SCHEMBL7552755 | 0.83 | CHRM2 (0.46) | CHRM2CHRM1CHRM3CYP1A2CYP3A4 | |
| SCHEMBL3432313 | 0.83 | CHRM2 (0.46) | CHRM2CHRM1CHRM3CYP1A2FDPS | |
| SCHEMBL7552787 | 0.82 | CHRNB2 (0.50) | CHRM2CHRM1CHRM3CYP1A2HSD11B1 | |
| SCHEMBL10202705 | 0.81 | CHRM2 (0.44) | CHRM2CHRM1CHRM3CYP1A2FDPS | |
| SCHEMBL7547862 | 0.81 | CHRNA7 (0.46) | CHRM2CHRM1CHRM3CYP1A2CYP3A4 | |
| SCHEMBL493020 | 0.80 | CYP1A2 (0.56) | CHRM2CHRM1CHRM3CYP1A2HSD11B1 | |
| SCHEMBL26806573 | 0.79 | CYP1A2 (0.47) | CYP1A2CYP3A4CYP2C9CYP2C19HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4630424-A1 | COMPOUNDS AND COMPOSITIONS AS C-KIT KINASE INHIBITORS | Third Harmonic Bio, Inc. (US) | 2025-10-15 | — | — | EP | disclosed |
| WO-2024124002-A1 | COMPOUNDS AND COMPOSITIONS AS C-KIT KINASE INHIBITORS | THIRD HARMONIC BIO, INC. (US) | 2024-06-13 | — | — | WO | disclosed |