Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
| ▸ | NEK2 | P51955 | 1/20 | 0.39 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | AOC1 | P19801 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3542027 | 1.00 | CHEK1 (0.39) | CHEK1NEK2LIMK1DYRK1ACLK4 | |
| SCHEMBL11320774 | 0.88 | CYP1A2 (0.43) | CHEK1NEK2LIMK1DYRK1ACLK4 | |
| SCHEMBL29986635 | 0.86 | CYP1A2 (0.42) | CHEK1NEK2LIMK1DYRK1ACLK4 | |
| SCHEMBL755230 | 0.83 | HRH3 (0.42) | CHEK1NEK2LIMK1DYRK1ACLK4 | |
| SCHEMBL5637004 | 0.83 | CHEK1 (0.42) | CHEK1NEK2LIMK1DYRK1ACLK4 | |
| SCHEMBL30450577 | 0.83 | CHEK1 (0.42) | CHEK1NEK2LIMK1DYRK1ACLK4 | |
| SCHEMBL2896836 | 0.81 | DRD3 (0.38) | CHEK1NEK2LIMK1DYRK1ACLK4 | |
| SCHEMBL2977480 | 0.80 | HTR2A (0.40) | CHEK1NEK2LIMK1DYRK1ACLK4 | |
| SCHEMBL14350994 | 0.80 | ALDH1A1 (0.39) | CHEK1NEK2LIMK1DYRK1ACLK4 | |
| SCHEMBL16117779 | 0.79 | CYP3A4 (0.38) | CHEK1NEK2LIMK1DYRK1ACLK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4608389-A2 | SUBSTITUTED PHENYLBENZENESULFONAMIDE DERIVATIVES AND USES THEREOF | Nine Square Therapeutics Corporation (US) | 2025-09-03 | — | — | EP | disclosed |
| WO-2024092235-A2 | SUBSTITUTED PHENYLBENZENESULFONAMIDE DERIVATIVES AND USES THEREOF | NINE SQUARE THERAPEUTICS CORPORATION (US) | 2024-05-02 | — | — | WO | disclosed |