SCHEMBL30936763

SCHEMBL30936763

CCc1cc(Nc2ncc(Cl)c(Nc3ccc(OC)cc3NS(C)(=O)=O)n2)c(OC)cc1N1CCC(N2CCNCC2)CC1

nearest known ligand 0.69

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ EGFR P00533 20/20 0.69
▸ MET P08581 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27076077 0.92 EGFR (0.60) EGFR
SCHEMBL30936850 0.91 EGFR (0.67) EGFRMET
SCHEMBL26906593 0.90 EGFR (0.69) EGFRMET
SCHEMBL30937107 0.89 EGFR (0.67) EGFR
SCHEMBL30936792 0.89 EGFR (0.59) EGFRMET
SCHEMBL30936937 0.89 EGFR (0.64) EGFRMET
SCHEMBL30936957 0.88 EGFR (0.67) EGFR
SCHEMBL30936756 0.88 EGFR (0.67) EGFRMET
SCHEMBL30936898 0.88 EGFR (0.67) EGFRMET
SCHEMBL30936923 0.88 EGFR (0.67) EGFRMET

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024072178-A1 COMPOUND FOR TARGETED PROTEIN DEGRADATION, AND USE THEREOF (주)사이러스테라퓨틱스 2024-04-04 — — WO disclosed
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