Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 19/20 | 0.67 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.54 |
| ▸ | ROS1 | P08922 | 1/20 | 0.52 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30936957 | 0.92 | EGFR (0.67) | EGFRLRRK2ROS1ALK | |
| SCHEMBL27076077 | 0.89 | EGFR (0.60) | EGFRLRRK2ALK | |
| SCHEMBL30936763 | 0.89 | EGFR (0.69) | EGFR | |
| SCHEMBL26906593 | 0.87 | EGFR (0.69) | EGFRALK | |
| SCHEMBL27076074 | 0.87 | EGFR (0.65) | EGFRLRRK2ROS1ALK | |
| SCHEMBL30936825 | 0.85 | EGFR (0.60) | EGFRLRRK2 | |
| SCHEMBL30936805 | 0.85 | EGFR (0.72) | EGFRALK | |
| SCHEMBL30936784 | 0.85 | EGFR (0.62) | EGFRALK | |
| SCHEMBL27076022 | 0.83 | EGFR (0.69) | EGFRLRRK2ROS1ALK | |
| SCHEMBL27076147 | 0.82 | EGFR (0.70) | EGFRALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024072178-A1 | COMPOUND FOR TARGETED PROTEIN DEGRADATION, AND USE THEREOF | (주)사이러스테라퓨틱스 | 2024-04-04 | — | — | WO | disclosed |