Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.54 |
| ▸ | CRBN | Q96SW2 | 11/20 | 0.51 |
| ▸ | IKZF3 | Q9UKT9 | 6/20 | 0.50 |
| ▸ | TNF | P01375 | 6/20 | 0.50 |
| ▸ | MAP1LC3B | Q9GZQ8 | 4/20 | 0.50 |
| ▸ | IL1B | P01584 | 4/20 | 0.50 |
| ▸ | DDB1 | Q16531 | 3/20 | 0.50 |
| ▸ | IKZF1 | Q13422 | 3/20 | 0.50 |
| ▸ | BRD4 | O60885 | 2/20 | 0.50 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21997340 | 0.89 | STAT3 (0.54) | STAT3CRBNIKZF3TNFMAP1LC3B | |
| SCHEMBL30936833 | 0.86 | STAT3 (0.52) | STAT3CRBNIKZF3TNFMAP1LC3B | |
| SCHEMBL30936795 | 0.85 | STAT3 (0.54) | STAT3CRBNIKZF3TNFMAP1LC3B | |
| SCHEMBL21998222 | 0.84 | STAT3 (0.58) | STAT3CRBNIKZF3TNFMAP1LC3B | |
| SCHEMBL25905191 | 0.82 | MAP1LC3B (0.66) | STAT3CRBNIKZF3TNFMAP1LC3B | |
| SCHEMBL30936855 | 0.82 | STAT3 (0.55) | STAT3CRBNIKZF3TNFMAP1LC3B | |
| SCHEMBL24207594 | 0.82 | STAT3 (0.61) | STAT3CRBNIKZF3TNFMAP1LC3B | |
| SCHEMBL17536588 | 0.82 | STAT3 (0.66) | STAT3CRBNIKZF3TNFMAP1LC3B | |
| Hydrochloric Acid SCHEMBL25327075 | 0.82 | MAP1LC3B (0.65) | STAT3CRBNIKZF3TNFMAP1LC3B | |
| SCHEMBL17536570 | 0.81 | CRBN (0.66) | STAT3CRBNIKZF3TNFMAP1LC3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024072178-A1 | COMPOUND FOR TARGETED PROTEIN DEGRADATION, AND USE THEREOF | (주)사이러스테라퓨틱스 | 2024-04-04 | — | — | WO | disclosed |