Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 15/20 | 0.65 |
| ▸ | ALK | Q9UM73 | 5/20 | 0.60 |
| ▸ | INSR | P06213 | 2/20 | 0.58 |
| ▸ | IGF1R | P08069 | 2/20 | 0.58 |
| ▸ | MET | P08581 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30937151 | 1.00 | EGFR (0.65) | EGFRALKINSRIGF1RMET | |
| SCHEMBL30936774 | 0.97 | EGFR (0.69) | EGFRALKINSRIGF1RMET | |
| SCHEMBL30937137 | 0.92 | EGFR (0.63) | EGFRALKINSRIGF1RMET | |
| SCHEMBL27076000 | 0.91 | EGFR (0.68) | EGFRALKINSRIGF1R | |
| SCHEMBL27076058 | 0.89 | ALK (0.72) | EGFRALKINSRIGF1RMET | |
| SCHEMBL30936898 | 0.89 | EGFR (0.67) | EGFRALKINSRIGF1RMET | |
| SCHEMBL30936888 | 0.86 | EGFR (0.65) | EGFRALKINSRIGF1R | |
| SCHEMBL27075961 | 0.84 | ALK (0.70) | EGFRALKINSRIGF1RMET | |
| SCHEMBL30936756 | 0.84 | EGFR (0.67) | EGFRALKMET | |
| SCHEMBL25305328 | 0.83 | EGFR (0.69) | EGFRALKINSRIGF1RMET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024072178-A1 | COMPOUND FOR TARGETED PROTEIN DEGRADATION, AND USE THEREOF | (주)사이러스테라퓨틱스 | 2024-04-04 | — | — | WO | disclosed |