Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 6/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.35 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.35 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30937050 | 1.00 | DPP4 (0.44) | DPP4MCHR1DPP8DPP7KCNH2 | |
| SCHEMBL24511505 | 0.93 | DPP4 (0.40) | DPP4MCHR1DPP8DPP7KCNH2 | |
| SCHEMBL24511675 | 0.91 | DPP4 (0.41) | DPP4MCHR1DPP8USP30 | |
| SCHEMBL24511489 | 0.91 | DPP4 (0.41) | DPP4MCHR1DPP8USP30 | |
| SCHEMBL24517987 | 0.91 | DPP4 (0.41) | DPP4MCHR1DPP8USP30 | |
| SCHEMBL30937160 | 0.89 | MEN1 (0.39) | DPP4MCHR1DPP8KCNH2DPP9 | |
| SCHEMBL30937051 | 0.86 | USP30 (0.38) | DPP4MCHR1DPP8KCNH2DPP9 | |
| SCHEMBL30937055 | 0.82 | DPP4 (0.47) | DPP4DPP7 | |
| SCHEMBL8584178 | 0.76 | DPP4 (0.45) | DPP4DPP7 | |
| SCHEMBL31097151 | 0.75 | HPGD (0.43) | USP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4608816-A1 | COMPOUNDS THAT MEDIATE PROTEIN DEGRADATION AND METHODS OF USE THEREOF | Monte Rosa Therapeutics AG (CH) | 2025-09-03 | — | — | EP | disclosed |
| WO-2024092039-A1 | COMPOUNDS THAT MEDIATE PROTEIN DEGRADATION AND METHODS OF USE THEREOF | MONTE ROSA THERAPEUTICS, INC. (US) | 2024-05-02 | — | — | WO | disclosed |