Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 18/20 | 0.54 |
| ▸ | MET | P08581 | 1/20 | 0.48 |
| ▸ | PLK1 | P53350 | 1/20 | 0.46 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30936861 | 0.93 | EGFR (0.62) | EGFRMET | |
| SCHEMBL30936893 | 0.88 | EGFR (0.56) | EGFRMETPLK1 | |
| SCHEMBL30776714 | 0.86 | EGFR (0.53) | EGFRMETPLK1LRRK2 | |
| SCHEMBL27039977 | 0.86 | EGFR (0.53) | EGFRMETPLK1LRRK2 | |
| SCHEMBL30776702 | 0.86 | EGFR (0.53) | EGFRMETPLK1LRRK2 | |
| SCHEMBL30936814 | 0.84 | EGFR (0.74) | EGFRMETPLK1LRRK2 | |
| SCHEMBL30958182 | 0.83 | EGFR (0.50) | EGFRMETPLK1LRRK2 | |
| SCHEMBL30936805 | 0.83 | EGFR (0.72) | EGFR | |
| SCHEMBL30776727 | 0.82 | ALK (0.46) | EGFRMETPLK1LRRK2 | |
| SCHEMBL30776707 | 0.82 | ALK (0.46) | EGFRMETPLK1LRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024072178-A1 | COMPOUND FOR TARGETED PROTEIN DEGRADATION, AND USE THEREOF | (주)사이러스테라퓨틱스 | 2024-04-04 | — | — | WO | disclosed |