SCHEMBL309376

SCHEMBL309376

Brc1sc2ccccc2c1Br

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 1/20 0.55
PTGS2 P35354 2/20 0.42
MAPT P10636 4/20 0.39
RAB9A P51151 4/20 0.39
ALDH1A1 P00352 3/20 0.39
HPGD P15428 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
LOXL2 Q9Y4K0 1/20 0.38
ALOX15 P16050 1/20 0.38
MEN1 O00255 3/20 0.37
KMT2A Q03164 3/20 0.37
NPC1 O15118 2/20 0.37
GAA P10253 1/20 0.37
MAPK1 P28482 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
PTPN1 P18031 1/20 0.37
HDAC1 Q13547 1/20 0.36
HDAC8 Q9BY41 1/20 0.36
HDAC6 Q9UBN7 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29434786 1.00 GPR3 (0.55) GPR3PTGS2MAPTRAB9AALDH1A1
SCHEMBL19135547 0.83 GPR3 (0.52) GPR3PTGS2MAPTRAB9AALDH1A1
SCHEMBL24442088 0.81 GPR3 (0.50) GPR3PTGS2MAPTRAB9AALDH1A1
SCHEMBL31337819 0.81 GPR3 (0.50) GPR3PTGS2MAPTRAB9AALDH1A1
SCHEMBL23870646 0.81 GPR3 (0.50) GPR3PTGS2MAPTRAB9AALDH1A1
SCHEMBL1518983 0.80 GPR3 (0.55) GPR3PTGS2MAPTRAB9AALDH1A1
SCHEMBL10053261 0.80 GPR3 (0.55) GPR3PTGS2MAPTRAB9AALDH1A1
SCHEMBL17340896 0.78 GPR3 (0.46) GPR3PTGS2MAPTRAB9AALDH1A1
SCHEMBL28494462 0.76 GPR3 (0.50) GPR3PTGS2MAPTRAB9AALDH1A1
SCHEMBL28479943 0.76 MAPT (0.52) GPR3MAPTRAB9AALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 106 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115650951-B Diaryl ethylene organic photochromic material and preparation method thereof 中国人民解放军96901部队25分队 2023-12-26 CN claimed
CN-115650951-A Diaryl ethylene organic photochromic material and preparation method thereof 中国人民解放军96901部队25分队 2023-01-31 CN claimed
CN-108172330-B Longitudinal watertight cable 扬州市金鑫电缆有限公司 2021-03-16 CN claimed
WO-2025110081-A1 COMPOUND, LIGHT-EMITTING ELEMENT CONTAINING SAME, DISPLAY DEVICE, AND ILLUMINATION DEVICE 東レ株式会社 2025-05-30 WO disclosed
WO-2024248977-A1 PHOTOACTIVE COMPOUNDS FOR VAPOR DEPOSITED STABLE ORGANIC PHOTOVOLTAIC DEVICES UBIQUITOUS ENERGY, INC. (US) 2024-12-05 WO disclosed
US-20240301286-A1 ORGANIC COMPOUND AND USE THEREOF, PASSIVATION FILM, SOLAR BATTERY, AND ELECTRICAL APPARATUS CONTEMPORARY AMPEREX TECHNOLOGY (HONG KONG) LIMITED (CN) 2024-09-12 US disclosed
WO-2024122572-A1 WAVELENGTH CONVERSION FILM-FORMING COMPOSITION AND FUSED THIOPHENE COMPOUND 日産化学株式会社 2024-06-13 WO disclosed
EP-4349808-A1 ORGANIC COMPOUND AND USE THEREOF, PASSIVATION FILM, SOLAR CELL AND ELECTRONIC DEVICE Contemporary Amperex Technology Co., Limited (CN) 2024-04-10 EP disclosed
CN-117836265-A Organic compound and application thereof, passivation film, solar cell and power utilization device 宁德时代新能源科技股份有限公司 2024-04-05 CN disclosed
CN-115650951-B Diaryl ethylene organic photochromic material and preparation method thereof 中国人民解放军96901部队25分队 2023-12-26 CN disclosed
WO-2023226000-A1 ORGANIC COMPOUND AND USE THEREOF, PASSIVATION FILM, SOLAR CELL AND ELECTRONIC DEVICE 宁德时代新能源科技股份有限公司 2023-11-30 WO disclosed
US-20050107248-A1 Metallic catalysts for chemo-, regio-and stereoselective reactions, and corresponding precursors CHEMI S.P.A. (IT) 2005-05-19 US disclosed
EP-1490173-A2 METALORGANIC CATALYSTS FOR CHEMO-, REGIO- AND STEREOSELECTIVE REACTIONS, AND CORRESPONDING PRECURSORS CHEMI S.p.A. (IT) 2004-12-29 EP disclosed
WO-2003074169-A2 METALORGANIC CATALYSTS FOR CHEMO-, REGIO- AND STEREOSELECTIVE REACTIONS, AND CORRESPONDING PRECURSORS CHEMI S.P.A. (IT) 2003-09-12 WO disclosed
EP-0997460-B1 Benzothiophene compounds as antithrombotic agents and intermediates LILLY CO ELI (US) 2002-12-11 EP disclosed
US-6133262-A 3-AMINOBENZO(B)THIOPHENE DERIVATIVES ELI LILLY AND COMPANY (US) 2000-10-17 US disclosed
EP-0997460-A1 Benzothiophene compounds as antithrombotic agents and intermediates ELI LILLY AND COMPANY (US) 2000-05-03 EP disclosed
EP-0217530-B1 DIHYDROPYRIDINES ELI LILLY AND COMPANY (US) 1990-10-31 EP disclosed
US-4659717-A CAUSING VASODILATION ELI LILLY AND COMPANY (US) 1987-04-21 US disclosed
EP-0217530-A1 Dihydropyridines ELI LILLY AND COMPANY (US) 1987-04-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050107248-A1 Metallic catalysts for chemo-, regio-and stereoselective reactions, and corresponding precursors PHOSPHO1, OSTC, MAS1 GPR3 742/4885PTGS2 3651/4885MAPT 4461/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.