Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.54 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.53 |
| ▸ | FAAH | O00519 | 6/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.45 |
| ▸ | CNR1 | P21554 | 2/20 | 0.45 |
| ▸ | CNR2 | P34972 | 2/20 | 0.45 |
| ▸ | CES2 | O00748 | 3/20 | 0.42 |
| ▸ | CES1 | P23141 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2869814 | 1.00 | EPHX2 (0.54) | EPHX2SPHK1FAAHMEN1MAPK1 | |
| SCHEMBL20338594 | 0.84 | EPHX2 (0.56) | EPHX2SPHK1FAAHMEN1MAPK1 | |
| SCHEMBL27585282 | 0.77 | EPHX2 (0.45) | EPHX2SPHK1FAAHMEN1MAPK1 | |
| SCHEMBL15285134 | 0.75 | SPHK1 (0.65) | EPHX2SPHK1FAAHMEN1MAPK1 | |
| SCHEMBL15297190 | 0.75 | SPHK1 (0.65) | EPHX2SPHK1FAAHMEN1MAPK1 | |
| SCHEMBL15297852 | 0.75 | SPHK1 (0.65) | EPHX2SPHK1FAAHMEN1MAPK1 | |
| SCHEMBL27760068 | 0.75 | SPHK1 (0.52) | EPHX2SPHK1FAAHMEN1MAPK1 | |
| SCHEMBL29242051 | 0.74 | EPHX2 (0.45) | EPHX2SPHK1FAAHMEN1MAPK1 | |
| SCHEMBL13146756 | 0.74 | EPHX2 (0.45) | EPHX2SPHK1FAAHMEN1MAPK1 | |
| SCHEMBL27715354 | 0.74 | SPHK1 (0.55) | EPHX2SPHK1FAAHMEN1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170359965-A1 | POLYLACTIC ACID COMPOSITIONS WITH ACCELERATED DEGRADATION RATE AND INCREASED HEAT STABILITY | DU PONT (US) | 2017-12-21 | — | — | US | disclosed |
| US-20140309379-A1 | POLYSILOXANE-MODIFIED POLYLACTIC ACID COMPOSITION, COMPOSITION UTILIZING SAME, MOLDED ARTICLE, AND PRODUCTION METHOD | NEC CORPORATION (JP) | 2014-10-16 | — | — | US | disclosed |
| US-8779042-B2 | Flame-retardant polylactic acid based resin composition, molded article thereof and method for producing molded article | NEC CORPORATION (JP) | 2014-07-15 | — | — | US | disclosed |
| US-20130012631-A1 | FLAME-RETARDANT POLYLACTIC ACID BASED RESIN COMPOSITION, MOLDED ARTICLE THEREOF AND METHOD FOR PRODUCING MOLDED ARTICLE | NEC CORPORATION (JP) | 2013-01-10 | — | — | US | disclosed |
| US-20130005872-A1 | POLYLACTIC ACID RESIN COMPOSITION CONTAINING PHOSPHORUS COMPOUND AND POLYSILOXANE COMPOUND AND MOLDED ARTICLE MADE BY USING THE SAME | NEC CORPORATION (JP) | 2013-01-03 | — | — | US | disclosed |
| US-8202450-B2 | Flame retardant thermoplastic resin composition | NEC CORPORATION (JP) | 2012-06-19 | — | — | US | disclosed |
| US-20100311886-A1 | FLAME RETARDANT THERMOPLASTIC RESIN COMPOSITION TECHNICAL FIELD | NEC CORPORATION | 2010-12-09 | — | — | US | disclosed |
| US-7790069-B2 | Addition of aromatic ring containing compound and nucleating clay to metal hydrate and resin, improves fluidity, flame retardancy | NEC CORPORATION (JP) | 2010-09-07 | — | — | US | disclosed |
| US-20080071015-A1 | Addition of aromatic ring containing compound and nucleating clay to metal hydrate and resin, improves fluidity, flame retardancy | NEC CORPORATION (JP) | 2008-03-20 | — | — | US | disclosed |
| EP-1177784-B1 | Antiperspirant compositions | UNILEVER PLC (GB) | 2007-01-03 | — | — | EP | disclosed |
| US-6410003-B1 | ALKYLAMIDES DERIVED FROM TRANS-1,2-DIAMINOCYCLOHEXANE USED AS STRUCTURANTS | UNILEVER HOME & PERSONAL CARE USA DIVISION OF CONOPCO, INC. | 2002-06-25 | — | — | US | disclosed |
| US-20020037263-A1 | Alkylamides Derived from Trans-1,2-Diaminocyclohexane used as structurants | UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC | 2002-03-28 | — | — | US | disclosed |
| EP-1177784-A2 | Antiperspirant compositions | Unilever Plc (GB) | 2002-02-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020037263-A1 | Alkylamides Derived from Trans-1,2-Diaminocyclohexane used as structurants | SAT1, TAAR1, OPRM1 | EPHX2 2705/4885SPHK1 2993/4885FAAH 21/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.