Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | PLAT | P00750 | 7/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 3/20 | 0.34 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.34 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.34 |
| ▸ | PDE9A | O76083 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30938469 | 0.87 | KDM4E (0.37) | KDM4EHSD17B10ALDH1A1GAAHPGD | |
| SCHEMBL28555930 | 0.87 | PLAT (0.37) | PLATF2PDE9APDE4B | |
| SCHEMBL29227323 | 0.84 | PLAT (0.42) | KDM4EHSD17B10ALDH1A1GAAPLAT | |
| SCHEMBL30938493 | 0.79 | L3MBTL1 (0.39) | KDM4EHSD17B10PLATPIK3CAF2 | |
| SCHEMBL29227341 | 0.79 | KDM4E (0.40) | KDM4EHSD17B10ALDH1A1HPGDPLAT | |
| SCHEMBL28558132 | 0.74 | PLAT (0.39) | PLATF2PDE9APDE4B | |
| SCHEMBL28570653 | 0.73 | PLAT (0.39) | HSD17B10ALDH1A1HPGDPLATF2 | |
| SCHEMBL18057624 | 0.70 | KDM4E (0.43) | KDM4EHSD17B10ALDH1A1HPGDPLAT | |
| SCHEMBL18057626 | 0.69 | CSNK1D (0.43) | KDM4EHSD17B10ALDH1A1HPGDPLAT | |
| SCHEMBL29227412 | 0.68 | PLAT (0.34) | HSD17B10ALDH1A1HPGDPLATF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112778311-B | Nitrogen-containing fused ring derivative inhibitor, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2024-06-04 | — | — | CN | disclosed |