Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 7/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | MAPT | P10636 | 4/20 | 0.60 |
| ▸ | CYP26A1 | O43174 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 4/20 | 0.57 |
| ▸ | RAB9A | P51151 | 4/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.57 |
| ▸ | CYP27A1 | Q02318 | 1/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.57 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.57 |
| ▸ | RELA | Q04206 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29946409 | 1.00 | MIF (0.63) | MIFSMN1; SMN2ALDH1A1MAPTCYP26A1 | |
| SCHEMBL7001015 | 1.00 | MIF (0.63) | MIFSMN1; SMN2ALDH1A1MAPTCYP26A1 | |
| SCHEMBL7001016 | 1.00 | MIF (0.63) | MIFSMN1; SMN2ALDH1A1MAPTCYP26A1 | |
| SCHEMBL17571252 | 0.90 | MAOB (0.64) | MIFSMN1; SMN2ALDH1A1MAPTCYP26A1 | |
| SCHEMBL6990658 | 0.90 | MAOB (0.64) | MIFSMN1; SMN2ALDH1A1MAPTCYP26A1 | |
| SCHEMBL6990660 | 0.90 | MAOB (0.64) | MIFSMN1; SMN2ALDH1A1MAPTCYP26A1 | |
| SCHEMBL6361514 | 0.82 | MIF (0.67) | MIFSMN1; SMN2ALDH1A1MAPTCYP26A1 | |
| SCHEMBL7517262 | 0.82 | MIF (0.66) | MIFSMN1; SMN2ALDH1A1MAPTCYP26A1 | |
| SCHEMBL12760787 | 0.82 | MIF (0.67) | MIFSMN1; SMN2ALDH1A1MAPTCYP26A1 | |
| SCHEMBL1814542 | 0.81 | MIF (0.48) | MIFSMN1; SMN2ALDH1A1MAPTCYP26A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118184606-A | Method for preparing 2, 5-disubstituted and 2,3, 5-trisubstituted furan skeleton derivative | 中国医学科学院药物研究所 | 2024-06-14 | — | — | CN | disclosed |