Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 2/20 | 0.40 |
| ▸ | CASP7 | P55210 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | FEN1 | P39748 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29262316 | 1.00 | CASP1 (0.40) | CASP1CASP7HSD17B10OPRK1TSHR | |
| SCHEMBL22392052 | 1.00 | CASP1 (0.40) | CASP1CASP7HSD17B10OPRK1TSHR | |
| SCHEMBL32669487 | 0.91 | CASP1 (0.40) | CASP1CASP7HSD17B10OPRK1TSHR | |
| SCHEMBL22392010 | 0.91 | CASP1 (0.40) | CASP1CASP7HSD17B10OPRK1TSHR | |
| SCHEMBL22009782 | 0.90 | GLP1R (0.36) | CASP1CASP7HSD17B10TSHRKDM4E | |
| SCHEMBL30174474 | 0.90 | GLP1R (0.36) | CASP1CASP7HSD17B10TSHRKDM4E | |
| SCHEMBL29097938 | 0.90 | GLP1R (0.36) | CASP1CASP7HSD17B10TSHRKDM4E | |
| SCHEMBL22392029 | 0.86 | KCNH2 (0.38) | CASP1CASP7HSD17B10OPRK1TSHR | |
| SCHEMBL22527886 | 0.85 | GLP1R (0.39) | KDM4EGLA | |
| SCHEMBL22061831 | 0.85 | GLP1R (0.39) | KDM4EGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113853371-B | GLP-1R agonists and uses thereof | 上海齐鲁锐格医药研发有限公司 | 2024-05-03 | — | — | CN | disclosed |