Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 9/20 | 0.63 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.63 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.51 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.51 |
| ▸ | MAOB | P27338 | 6/20 | 0.51 |
| ▸ | MAOA | P21397 | 4/20 | 0.51 |
| ▸ | APP | P05067 | 1/20 | 0.49 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30938831 | 1.00 | PTGS2 (0.63) | PTGS2PTGS1KEAP1NFE2L2MAOB | |
| SCHEMBL30938832 | 0.92 | PTGS2 (0.52) | PTGS2PTGS1MAOBMAOACHRNA7 | |
| SCHEMBL30938829 | 0.92 | PTGS2 (0.52) | PTGS2PTGS1MAOBMAOACHRNA7 | |
| SCHEMBL30938828 | 0.89 | SMN1; SMN2 (0.52) | PTGS2PTGS1MAOBMAOA | |
| SCHEMBL31026421 | 0.77 | MAOB (0.68) | PTGS2PTGS1MAOBMAOAAPP | |
| SCHEMBL31026429 | 0.75 | PTGS2 (0.61) | PTGS2PTGS1KEAP1NFE2L2MAOB | |
| SCHEMBL31026445 | 0.75 | MAOB (0.69) | PTGS2MAOBMAOA | |
| SCHEMBL28603606 | 0.75 | MAOB (0.68) | PTGS2PTGS1MAOBMAOA | |
| SCHEMBL31026419 | 0.75 | PTGS2 (0.56) | PTGS2MAOBMAOAAPP | |
| SCHEMBL31026427 | 0.75 | MAOB (0.70) | PTGS2MAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118125997-A | Pterocarpus stilbene paeonol chalcone amide derivative, preparation method and medical application thereof | 安徽中医药大学 | 2024-06-04 | — | — | CN | disclosed |