Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 9/20 | 0.55 |
| ▸ | DDB1 | Q16531 | 5/20 | 0.47 |
| ▸ | HPGDS | O60760 | 2/20 | 0.47 |
| ▸ | TMEM97 | Q5BJF2 | 10/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 10/20 | 0.44 |
| ▸ | HRH2 | P25021 | 4/20 | 0.44 |
| ▸ | HRH1 | P35367 | 4/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.44 |
| ▸ | HTR1A | P08908 | 3/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.44 |
| ▸ | HTR2C | P28335 | 3/20 | 0.44 |
| ▸ | HTR2A | P28223 | 2/20 | 0.44 |
| ▸ | HTR2B | P41595 | 2/20 | 0.44 |
| ▸ | DRD3 | P35462 | 2/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.44 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.44 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29927356 | 0.88 | CRBN (0.57) | CRBNDDB1HPGDSIKZF3 | |
| SCHEMBL29132159 | 0.88 | CRBN (0.57) | CRBNDDB1HPGDSIKZF3 | |
| SCHEMBL31043982 | 0.87 | CRBN (0.58) | CRBNDDB1HPGDSTMEM97SIGMAR1 | |
| SCHEMBL29927342 | 0.86 | CRBN (0.55) | CRBNDDB1HPGDSTMEM97SIGMAR1 | |
| SCHEMBL31043971 | 0.85 | CRBN (0.56) | CRBNDDB1HPGDS | |
| SCHEMBL30683384 | 0.84 | CRBN (0.56) | CRBNDDB1HPGDSIKZF3ALDH1A1 | |
| SCHEMBL27035713 | 0.84 | CRBN (0.56) | CRBNDDB1HPGDSIKZF3ALDH1A1 | |
| SCHEMBL30683380 | 0.84 | CRBN (0.56) | CRBNDDB1HPGDSIKZF3ALDH1A1 | |
| SCHEMBL22291366 | 0.84 | CRBN (0.54) | CRBNDDB1HPGDSIKZF3 | |
| SCHEMBL29547197 | 0.84 | CRBN (0.54) | CRBNDDB1HPGDSTMEM97SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4630414-A1 | TARGETED PROTEIN DEGRADATION USING BIFUNCTIONAL COMPOUNDS THAT BIND UBIQUITIN LIGASE AND TARGET MCL-1 PROTEIN | Captor Therapeutics S.A. (PL) | 2025-10-15 | — | — | EP | disclosed |
| WO-2024121256-A1 | TARGETED PROTEIN DEGRADATION USING BIFUNCTIONAL COMPOUNDS THAT BIND UBIQUITIN LIGASE AND TARGET MCL-1 PROTEIN | CAPTOR THERAPEUTICS S.A. (PL) | 2024-06-13 | — | — | WO | disclosed |