Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | KDM1A | O60341 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | JAK1 | P23458 | 1/20 | 0.39 |
| ▸ | TYK2 | P29597 | 1/20 | 0.39 |
| ▸ | JAK3 | P52333 | 1/20 | 0.39 |
| ▸ | BTK | Q06187 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29850045 | 1.00 | MAOB (0.46) | MAOBKDM1ADRD2SMN1; SMN2CTDSP1 | |
| SCHEMBL29849710 | 0.88 | MAOB (0.44) | MAOBKDM1ADRD2SMN1; SMN2CTDSP1 | |
| SCHEMBL31514885 | 0.86 | KDM1A (0.45) | MAOBKDM1ADRD2EPHX2JAK2 | |
| SCHEMBL30810403 | 0.86 | KDM1A (0.45) | MAOBKDM1ADRD2EPHX2JAK2 | |
| SCHEMBL31155693 | 0.82 | CCR6 (0.55) | MAOBKDM1ADRD2EPHX2KAT6A | |
| SCHEMBL1867760 | 0.81 | TGM2 (0.51) | MAOBKDM1A | |
| SCHEMBL5311837 | 0.81 | EPHX2 (0.58) | SMN1; SMN2ALDH1A1EPHX2KMT2AGAA | |
| SCHEMBL29849905 | 0.80 | AAK1 (0.43) | MAOBKDM1ADRD2MAOAJAK2 | |
| SCHEMBL23720467 | 0.79 | KDM1A (0.49) | MAOBKDM1ADRD2SMN1; SMN2ALDH1A1 | |
| SCHEMBL30556445 | 0.79 | KDM1A (0.49) | MAOBKDM1ADRD2SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4630402-A1 | SULFONYL DERIVATIVES AS CCR6 INHIBITORS | F. Hoffmann-La Roche AG (CH) | 2025-10-15 | — | — | EP | disclosed |
| WO-2024121013-A1 | SULFONYL DERIVATIVES AS CCR6 INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2024-06-13 | — | — | WO | disclosed |