Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD52 | P43351 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | POLB | P06746 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | GAA | P10253 | 5/20 | 0.37 |
| ▸ | GLA | P06280 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.37 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1019383 | 0.82 | IP6K1 (0.47) | RAD52KMT2APOLBKDM4EALDH1A1 | |
| SCHEMBL30939423 | 0.77 | RAD52 (0.37) | RAD52KMT2APOLBKDM4EALDH1A1 | |
| SCHEMBL30850601 | 0.76 | RECQL (0.48) | KMT2AKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL3026520 | 0.73 | CDK2 (0.60) | KMT2APDPK1NTRK1MAPTRAB9A | |
| SCHEMBL15690 | 0.72 | SMN1; SMN2 (0.49) | KMT2APOLBKDM4EALDH1A1ALOX15 | |
| SCHEMBL4411497 | 0.72 | SMN1; SMN2 (0.49) | KMT2AKDM4EALDH1A1ALOX15HSD17B10 | |
| SCHEMBL5934350 | 0.70 | HTT (0.40) | KMT2AALDH1A1GLAHPGDHSD17B10 | |
| SCHEMBL16873181 | 0.70 | CYP3A4 (0.40) | RAD52KMT2APOLBKDM4EALDH1A1 | |
| SCHEMBL8542827 | 0.70 | HDAC6 (0.44) | KDM4EALDH1A1GAAGLAHPGD | |
| SCHEMBL6885719 | 0.69 | GAA (0.36) | KMT2AKDM4EALDH1A1GAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118130677-A | Method for detecting 6-thioguanine by rapid and high-efficiency chemical derivatization-high performance liquid chromatography | 重庆医科大学国际体外诊断研究院 | 2024-06-04 | — | — | CN | claimed |
| CN-118130677-A | Method for detecting 6-thioguanine by rapid and high-efficiency chemical derivatization-high performance liquid chromatography | 重庆医科大学国际体外诊断研究院 | 2024-06-04 | — | — | CN | disclosed |