Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD52 | P43351 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | APP | P05067 | 6/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | UBE2N | P61088 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 2/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30939422 | 0.77 | RAD52 (0.39) | RAD52KMT2APOLBAPPKDM4E | |
| SCHEMBL9076301 | 0.68 | SMN1; SMN2 (0.41) | RAD52KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL16146949 | 0.67 | ADORA3 (0.44) | KMT2APOLBKDM4EALDH1A1MAPT | |
| SCHEMBL16147020 | 0.67 | PDE4A (0.47) | KMT2A | |
| SCHEMBL13729103 | 0.66 | APP (0.54) | APPMAPTNPSR1GAA | |
| SCHEMBL16146131 | 0.66 | CDK1 (0.47) | RAD52KMT2AAPPKDM4EALDH1A1 | |
| SCHEMBL8369493 | 0.66 | CDK1 (0.44) | RAD52LMNA | |
| SCHEMBL27603868 | 0.65 | RAD52 (0.68) | RAD52KMT2APOLBAPPKDM4E | |
| SCHEMBL1275415 | 0.63 | KDM4E (0.31) | KMT2AKDM4EALDH1A1GAAHPGD | |
| SCHEMBL5103819 | 0.63 | CNR2 (0.43) | KMT2APOLBAPPKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118130677-A | Method for detecting 6-thioguanine by rapid and high-efficiency chemical derivatization-high performance liquid chromatography | 重庆医科大学国际体外诊断研究院 | 2024-06-04 | — | — | CN | claimed |
| CN-118130677-A | Method for detecting 6-thioguanine by rapid and high-efficiency chemical derivatization-high performance liquid chromatography | 重庆医科大学国际体外诊断研究院 | 2024-06-04 | — | — | CN | disclosed |