Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.38 |
| ▸ | IGF1R | P08069 | 1/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.38 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1978190 | 1.00 | LMNA (0.45) | LMNAMAPTALDH1A1HSD17B10KDM4C | |
| SCHEMBL30939545 | 0.90 | MAPT (0.43) | LMNAMAPTALDH1A1HSD17B10KDM4C | |
| SCHEMBL1982553 | 0.90 | MAPT (0.43) | LMNAMAPTALDH1A1HSD17B10KDM4C | |
| SCHEMBL1978849 | 0.85 | DRD1 (0.40) | MAPTALDH1A1HSD17B10KDM4CMEN1 | |
| SCHEMBL30939609 | 0.85 | DRD1 (0.40) | MAPTALDH1A1HSD17B10KDM4CMEN1 | |
| SCHEMBL1979642 | 0.84 | LMNA (0.67) | LMNAMAPTALDH1A1HSD17B10KDM4C | |
| SCHEMBL30939549 | 0.84 | LMNA (0.67) | LMNAMAPTALDH1A1HSD17B10KDM4C | |
| SCHEMBL30939557 | 0.83 | LMNA (0.52) | LMNAMAPTALDH1A1HSD17B10KDM4C | |
| SCHEMBL1980208 | 0.83 | LMNA (0.52) | LMNAMAPTALDH1A1HSD17B10KDM4C | |
| SCHEMBL21581670 | 0.82 | KDM4C (0.35) | MAPTALDH1A1HSD17B10KDM4CTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118267386-A | Modulators of KV3 channels for the treatment of pain | 奥提芙尼治疗学有限公司 | 2024-07-02 | — | — | CN | disclosed |
| CN-108472288-B | Modulators of KV3 channels for the treatment of pain | 奥提芙尼治疗学有限公司 | 2024-05-28 | — | — | CN | disclosed |