Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HASPIN | Q8TF76 | 5/20 | 0.64 |
| ▸ | DYRK2 | Q92630 | 2/20 | 0.64 |
| ▸ | DYRK1A | Q13627 | 15/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.45 |
| ▸ | CLK1 | P49759 | 1/20 | 0.45 |
| ▸ | CLK2 | P49760 | 1/20 | 0.45 |
| ▸ | CLK3 | P49761 | 1/20 | 0.45 |
| ▸ | GSK3B | P49841 | 1/20 | 0.45 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.45 |
| ▸ | DYRK4 | Q9NR20 | 1/20 | 0.45 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16123504 | 1.00 | HASPIN (0.64) | HASPINDYRK2DYRK1AHTR2AHTR2C | |
| SCHEMBL16126053 | 0.86 | HASPIN (0.46) | HASPINDYRK2DYRK1AHTR2AHTR2C | |
| SCHEMBL16123610 | 0.85 | HASPIN (0.45) | HASPINDYRK2DYRK1AHTR2AHTR2C | |
| SCHEMBL30939924 | 0.85 | HASPIN (0.45) | HASPINDYRK2DYRK1AHTR2AHTR2C | |
| SCHEMBL16123598 | 0.85 | DYRK1A (0.69) | HASPINDYRK1AHTR2AHTR2CACHE | |
| SCHEMBL30940009 | 0.85 | DYRK1A (0.69) | HASPINDYRK1AHTR2AHTR2CACHE | |
| SCHEMBL30939975 | 0.83 | DYRK1A (0.72) | HASPINDYRK2DYRK1AHTR2AHTR2C | |
| SCHEMBL16123609 | 0.83 | DYRK1A (0.72) | HASPINDYRK2DYRK1AHTR2AHTR2C | |
| SCHEMBL16123511 | 0.82 | HASPIN (0.60) | HASPINDYRK2DYRK1AHTR2AHTR2C | |
| SCHEMBL30939909 | 0.82 | HASPIN (0.60) | HASPINDYRK2DYRK1AHTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113416187-B | Alkylamine harmine derivatives for promoting bone growth | 奥斯菲治疗有限公司 | 2024-07-19 | — | — | CN | disclosed |