Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HASPIN | Q8TF76 | 5/20 | 0.64 |
| ▸ | DYRK2 | Q92630 | 2/20 | 0.64 |
| ▸ | DYRK1A | Q13627 | 15/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.45 |
| ▸ | CLK1 | P49759 | 1/20 | 0.45 |
| ▸ | CLK2 | P49760 | 1/20 | 0.45 |
| ▸ | CLK3 | P49761 | 1/20 | 0.45 |
| ▸ | GSK3B | P49841 | 1/20 | 0.45 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.45 |
| ▸ | DYRK4 | Q9NR20 | 1/20 | 0.45 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30939918 | 1.00 | HASPIN (0.64) | HASPINDYRK2DYRK1AHTR2AHTR2C | |
| SCHEMBL16126053 | 0.86 | HASPIN (0.46) | HASPINDYRK2DYRK1AHTR2AHTR2C | |
| SCHEMBL16123610 | 0.85 | HASPIN (0.45) | HASPINDYRK2DYRK1AHTR2AHTR2C | |
| SCHEMBL30939924 | 0.85 | HASPIN (0.45) | HASPINDYRK2DYRK1AHTR2AHTR2C | |
| SCHEMBL16123598 | 0.85 | DYRK1A (0.69) | HASPINDYRK1AHTR2AHTR2CACHE | |
| SCHEMBL30940009 | 0.85 | DYRK1A (0.69) | HASPINDYRK1AHTR2AHTR2CACHE | |
| SCHEMBL30939975 | 0.83 | DYRK1A (0.72) | HASPINDYRK2DYRK1AHTR2AHTR2C | |
| SCHEMBL16123609 | 0.83 | DYRK1A (0.72) | HASPINDYRK2DYRK1AHTR2AHTR2C | |
| SCHEMBL16123511 | 0.82 | HASPIN (0.60) | HASPINDYRK2DYRK1AHTR2AHTR2C | |
| SCHEMBL30939909 | 0.82 | HASPIN (0.60) | HASPINDYRK2DYRK1AHTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2968284-B1 | ALKYL-AMINE HARMINE DERIVATIVES FOR PROMOTING BONE GROWTH | OSTEOQC INC (CA) | 2021-04-21 | — | — | EP | claimed |
| EP-3915987-B1 | ALKYL-AMINE HARMINE DERIVATIVES FOR PROMOTING BONE GROWTH | OSTEOQC INC (CA) | 2023-12-13 | — | — | EP | disclosed |
| EP-3915987-B1 | ALKYL-AMINE HARMINE DERIVATIVES FOR PROMOTING BONE GROWTH | OSTEOQC INC (CA) | 2023-12-13 | — | — | EP | disclosed |
| EP-3915987-A1 | ALKYL-AMINE HARMINE DERIVATIVES FOR PROMOTING BONE GROWTH | Osteoqc Inc. (CA) | 2021-12-01 | — | — | EP | disclosed |
| EP-2968284-B1 | ALKYL-AMINE HARMINE DERIVATIVES FOR PROMOTING BONE GROWTH | OSTEOQC INC (CA) | 2021-04-21 | — | — | EP | disclosed |
| US-20200172538-A1 | COMPOUNDS FOR BONE GROWTH | OSSIFI THERAPEUTICS LLC | 2020-06-04 | — | — | US | disclosed |
| US-20200172538-A1 | COMPOUNDS FOR BONE GROWTH | OSSIFI THERAPEUTICS LLC | 2020-06-04 | — | — | US | disclosed |
| US-20170298059-A1 | COMPOUNDS FOR BONE GROWTH | OSSIFI THERAPEUTICS LLC | 2017-10-19 | — | — | US | disclosed |
| US-20170298059-A1 | COMPOUNDS FOR BONE GROWTH | OSSIFI THERAPEUTICS LLC | 2017-10-19 | — | — | US | disclosed |
| US-9540365-B2 | Compounds for bone growth | OSTEOQC INC. (CA) | 2017-01-10 | — | — | US | disclosed |
| US-9540365-B2 | Compounds for bone growth | OSTEOQC INC. (CA) | 2017-01-10 | — | — | US | disclosed |
| WO-2014153203-A2 | ALKYL-AMINE HARMINE DERIVATIVES FOR PROMOTING BONE GROWTH | OSSIFI INC. (US) | 2014-09-25 | — | — | WO | disclosed |
| US-20140288068-A1 | ALKYL-AMINE HARMINE DERIVATIVES FOR PROMOTING BONE GROWTH | OSSIFI INC. (US) | 2014-09-25 | — | — | US | disclosed |
| US-20140288068-A1 | ALKYL-AMINE HARMINE DERIVATIVES FOR PROMOTING BONE GROWTH | OSSIFI INC. (US) | 2014-09-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200172538-A1 | COMPOUNDS FOR BONE GROWTH | FGF1, FGF2, BMP2 | HASPIN 1246/4885DYRK2 4607/4885DYRK1A 4508/4885 |
| US-20170298059-A1 | COMPOUNDS FOR BONE GROWTH | FGF1, FGF2, BMP2 | HASPIN 1246/4885DYRK2 4607/4885DYRK1A 4508/4885 |
| US-20140288068-A1 | ALKYL-AMINE HARMINE DERIVATIVES FOR PROMOTING BONE GROWTH | TPH1, TPH2, HTR5A | HASPIN 696/4885DYRK2 3323/4885DYRK1A 3234/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.