Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HASPIN | Q8TF76 | 2/20 | 0.46 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.46 |
| ▸ | XDH | P47989 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | NCF1 | P14598 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | CXCR4 | P61073 | 7/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | METAP2 | P50579 | 1/20 | 0.33 |
| ▸ | KDM5C | P41229 | 1/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16102546 | 1.00 | HASPIN (0.46) | HASPINDYRK2XDHDYRK1AADRB2 | |
| SCHEMBL30939883 | 0.94 | HASPIN (0.49) | HASPINDYRK2XDHDYRK1AADRB2 | |
| SCHEMBL16102630 | 0.94 | HASPIN (0.49) | HASPINDYRK2XDHDYRK1AADRB2 | |
| SCHEMBL30939917 | 0.90 | HASPIN (0.48) | HASPINDYRK2XDHGRIN1GRIN2B | |
| SCHEMBL16101221 | 0.90 | HASPIN (0.48) | HASPINDYRK2XDHGRIN1GRIN2B | |
| SCHEMBL16123614 | 0.88 | HASPIN (0.47) | HASPINDYRK2 | |
| SCHEMBL30939941 | 0.88 | HASPIN (0.47) | HASPINDYRK2 | |
| SCHEMBL16099108 | 0.85 | HASPIN (0.66) | HASPINDYRK2DYRK1A | |
| SCHEMBL30939900 | 0.85 | HASPIN (0.66) | HASPINDYRK2DYRK1A | |
| SCHEMBL16100331 | 0.84 | DYRK1A (0.48) | HASPINDYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113416187-B | Alkylamine harmine derivatives for promoting bone growth | 奥斯菲治疗有限公司 | 2024-07-19 | — | — | CN | disclosed |