SCHEMBL16100331

SCHEMBL16100331

Cc1nccc2c3ccc(O)cc3n(CCN3CCNCC3)c12

nearest known ligand 0.48

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
DYRK1A Q13627 16/20 0.48
HASPIN Q8TF76 5/20 0.46
HTR2A P28223 1/20 0.45
HTR2C P28335 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30939922 1.00 DYRK1A (0.48) DYRK1AHASPINHTR2AHTR2C
SCHEMBL16123663 0.94 DYRK1A (0.49) DYRK1AHASPIN
SCHEMBL30939935 0.94 DYRK1A (0.49) DYRK1AHASPIN
SCHEMBL16126051 0.89 DYRK1A (0.49) DYRK1AHASPINHTR2AHTR2C
SCHEMBL30939973 0.89 DYRK1A (0.49) DYRK1AHASPINHTR2AHTR2C
SCHEMBL16101335 0.89 DYRK1A (0.49) DYRK1AHASPINHTR2AHTR2C
SCHEMBL16099657 0.88 DYRK1A (0.48) DYRK1AHASPINHTR2AHTR2C
SCHEMBL30940010 0.88 DYRK1A (0.48) DYRK1AHASPINHTR2AHTR2C
SCHEMBL16123500 0.85 DYRK1A (0.69) DYRK1AHASPINHTR2AHTR2C
SCHEMBL30939994 0.85 DYRK1A (0.69) DYRK1AHASPINHTR2AHTR2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3915987-B1 ALKYL-AMINE HARMINE DERIVATIVES FOR PROMOTING BONE GROWTH OSTEOQC INC (CA) 2023-12-13 EP disclosed
EP-3915987-B1 ALKYL-AMINE HARMINE DERIVATIVES FOR PROMOTING BONE GROWTH OSTEOQC INC (CA) 2023-12-13 EP disclosed
US-11267814-B2 Compounds for bone growth OsteoQC, Inc. 2022-03-08 US disclosed
EP-3915987-A1 ALKYL-AMINE HARMINE DERIVATIVES FOR PROMOTING BONE GROWTH Osteoqc Inc. (CA) 2021-12-01 EP disclosed
EP-3915987-A1 ALKYL-AMINE HARMINE DERIVATIVES FOR PROMOTING BONE GROWTH Osteoqc Inc. (CA) 2021-12-01 EP disclosed
CN-113416187-A Alkylamine peganine derivatives for promoting bone growth 奥斯特克有限公司 2021-09-21 CN disclosed
CN-105120863-B Alkylamine peganine derivatives for promoting bone growth 奥斯特克有限公司 2021-06-04 CN disclosed
EP-2968284-B1 ALKYL-AMINE HARMINE DERIVATIVES FOR PROMOTING BONE GROWTH OSTEOQC INC (CA) 2021-04-21 EP disclosed
EP-2968284-B1 ALKYL-AMINE HARMINE DERIVATIVES FOR PROMOTING BONE GROWTH OSTEOQC INC (CA) 2021-04-21 EP disclosed
US-20200172538-A1 COMPOUNDS FOR BONE GROWTH OSSIFI THERAPEUTICS LLC 2020-06-04 US disclosed
US-20170298059-A1 COMPOUNDS FOR BONE GROWTH OSSIFI THERAPEUTICS LLC 2017-10-19 US disclosed
US-20170298059-A1 COMPOUNDS FOR BONE GROWTH OSSIFI THERAPEUTICS LLC 2017-10-19 US disclosed
US-20170298059-A1 COMPOUNDS FOR BONE GROWTH OSSIFI THERAPEUTICS LLC 2017-10-19 US disclosed
US-9540365-B2 Compounds for bone growth OSTEOQC INC. (CA) 2017-01-10 US disclosed
US-9540365-B2 Compounds for bone growth OSTEOQC INC. (CA) 2017-01-10 US disclosed
EP-2968284-A2 ALKYL-AMINE HARMINE DERIVATIVES FOR PROMOTING BONE GROWTH Osteoqc Inc. (CA) 2016-01-20 EP disclosed
WO-2014153203-A2 ALKYL-AMINE HARMINE DERIVATIVES FOR PROMOTING BONE GROWTH OSSIFI INC. (US) 2014-09-25 WO disclosed
WO-2014153203-A2 ALKYL-AMINE HARMINE DERIVATIVES FOR PROMOTING BONE GROWTH OSSIFI INC. (US) 2014-09-25 WO disclosed
US-20140288068-A1 ALKYL-AMINE HARMINE DERIVATIVES FOR PROMOTING BONE GROWTH OSSIFI INC. (US) 2014-09-25 US disclosed
US-20140288068-A1 ALKYL-AMINE HARMINE DERIVATIVES FOR PROMOTING BONE GROWTH OSSIFI INC. (US) 2014-09-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200172538-A1 COMPOUNDS FOR BONE GROWTH FGF1, FGF2, BMP2 DYRK1A 4508/4885HASPIN 1246/4885HTR2A 4576/4885
US-20170298059-A1 COMPOUNDS FOR BONE GROWTH FGF1, FGF2, BMP2 DYRK1A 4508/4885HASPIN 1246/4885HTR2A 4576/4885
US-11267814-B2 Compounds for bone growth FGF1, FGF2, BMP2 DYRK1A 4508/4885HASPIN 1246/4885HTR2A 4576/4885
US-20140288068-A1 ALKYL-AMINE HARMINE DERIVATIVES FOR PROMOTING BONE GROWTH TPH1, TPH2, HTR5A DYRK1A 3234/4885HASPIN 696/4885HTR2A 21/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.