Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPG | P10696 | 1/20 | 0.68 |
| ▸ | CSNK2A2 | P19784 | 4/20 | 0.47 |
| ▸ | CSNK2B | P67870 | 4/20 | 0.47 |
| ▸ | CSNK2A1 | P68400 | 4/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29954496 | 0.81 | ALPG (1.00) | ALPGCSNK2A2CSNK2BCSNK2A1MAPK1 | |
| SCHEMBL1611070 | 0.75 | ALPG (0.59) | ALPGCSNK2A2CSNK2BCSNK2A1MAPK1 | |
| SCHEMBL19217398 | 0.73 | CSNK2A2 (0.62) | ALPGCSNK2A2CSNK2BCSNK2A1MAPK1 | |
| SCHEMBL21467921 | 0.72 | CSNK2A2 (0.50) | ALPGCSNK2A2CSNK2BCSNK2A1MAPK1 | |
| SCHEMBL3196866 | 0.72 | CA2 (0.57) | ALPGCSNK2A2CSNK2BCSNK2A1MAPK1 | |
| SCHEMBL29958053 | 0.72 | NQO1 (0.61) | ALPGCSNK2A2CSNK2BCSNK2A1MAPK1 | |
| SCHEMBL10436941 | 0.72 | NQO1 (0.61) | ALPGCSNK2A2CSNK2BCSNK2A1MAPK1 | |
| SCHEMBL6471096 | 0.70 | ALPG (0.62) | ALPGCSNK2A2CSNK2BCSNK2A1MAPK1 | |
| SCHEMBL2628177 | 0.70 | CSNK2A2 (0.58) | ALPGCSNK2A2CSNK2BCSNK2A1MAPK1 | |
| SCHEMBL8713331 | 0.70 | PTPN1 (0.49) | ALPGCSNK2A2CSNK2BCSNK2A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118359631-A | Polycyclic PI3K alpha inhibitors | 轩竹生物科技股份有限公司 | 2024-07-19 | — | — | CN | disclosed |