Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 7/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.37 |
| ▸ | CDK2 | P24941 | 4/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.32 |
| ▸ | SRD5A1 | P18405 | 2/20 | 0.32 |
| ▸ | DHODH | Q02127 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30940294 | 0.90 | PIK3CA (0.37) | PIK3CAPIK3CBCDK2SRD5A1DHODH | |
| SCHEMBL30940300 | 0.83 | SRD5A1 (0.34) | PIK3CACDK2MAPK14SRD5A1DHODH | |
| SCHEMBL30940312 | 0.82 | DHODH (0.34) | PIK3CACDK2MAPK14SRD5A1DHODH | |
| SCHEMBL30940286 | 0.81 | PIK3CA (0.65) | PIK3CAPIK3CB | |
| SCHEMBL30940295 | 0.80 | PIK3CA (0.39) | PIK3CAMAPK14DHODHSMN1; SMN2 | |
| SCHEMBL31145034 | 0.78 | PIK3CA (0.63) | PIK3CAPIK3CB | |
| SCHEMBL31144994 | 0.78 | PIK3CA (0.63) | PIK3CAPIK3CB | |
| SCHEMBL25185665 | 0.69 | PIK3CA (0.67) | PIK3CAPIK3CB | |
| SCHEMBL27135225 | 0.68 | PIK3CA (0.39) | PIK3CAPIK3CBCDK2 | |
| SCHEMBL26884309 | 0.68 | PIK3CA (0.39) | PIK3CAPIK3CBCDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118359631-A | Polycyclic PI3K alpha inhibitors | 轩竹生物科技股份有限公司 | 2024-07-19 | — | — | CN | disclosed |