Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 4/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.34 |
| ▸ | SRD5A1 | P18405 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | CDK2 | P24941 | 3/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.31 |
| ▸ | PTAFR | P25105 | 1/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31145023 | 0.86 | RAB9A (0.40) | PIK3CASMN1; SMN2TP53HSD17B10KDM4E | |
| SCHEMBL30940300 | 0.84 | SRD5A1 (0.34) | DHODHPIK3CASRD5A1SMN1; SMN2TP53 | |
| SCHEMBL30940290 | 0.82 | PIK3CA (0.39) | DHODHPIK3CASRD5A1SMN1; SMN2TP53 | |
| SCHEMBL30940294 | 0.80 | PIK3CA (0.37) | DHODHPIK3CASRD5A1CDK2 | |
| SCHEMBL30940286 | 0.76 | PIK3CA (0.65) | PIK3CA | |
| SCHEMBL30940295 | 0.75 | PIK3CA (0.39) | DHODHPIK3CASMN1; SMN2MAPK14NPC1 | |
| SCHEMBL31035315 | 0.72 | PIK3CA (0.61) | PIK3CASMN1; SMN2 | |
| SCHEMBL31284141 | 0.71 | MAPK14 (0.34) | MAPK14 | |
| SCHEMBL31284613 | 0.71 | RAB9A (0.42) | SMN1; SMN2TP53KDM4ENPC1ALDH1A1 | |
| SCHEMBL31145051 | 0.70 | ALDH1A1 (0.37) | PIK3CASMN1; SMN2TP53HSD17B10CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118359631-A | Polycyclic PI3K alpha inhibitors | 轩竹生物科技股份有限公司 | 2024-07-19 | — | — | CN | disclosed |