Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 16/20 | 0.49 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | JAK2 | O60674 | 4/20 | 0.36 |
| ▸ | JAK1 | P23458 | 3/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | JAK3 | P52333 | 1/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20985312 | 1.00 | TYK2 (0.49) | TYK2UGT1A1KCNH2JAK2JAK1 | |
| SCHEMBL30940522 | 0.86 | TYK2 (0.61) | TYK2UGT1A1KCNH2JAK2JAK1 | |
| SCHEMBL20985230 | 0.86 | TYK2 (0.61) | TYK2UGT1A1KCNH2JAK2JAK1 | |
| SCHEMBL20985343 | 0.81 | TYK2 (0.62) | TYK2UGT1A1KCNH2JAK2JAK1 | |
| SCHEMBL30940525 | 0.81 | TYK2 (0.62) | TYK2UGT1A1KCNH2JAK2JAK1 | |
| SCHEMBL20985220 | 0.78 | GRM5 (0.41) | TYK2PDE4DGRM5 | |
| SCHEMBL30940495 | 0.78 | GRM5 (0.41) | TYK2PDE4DGRM5 | |
| SCHEMBL20985285 | 0.76 | TYK2 (0.49) | TYK2UGT1A1KCNH2JAK2JAK1 | |
| SCHEMBL30940515 | 0.76 | TYK2 (0.49) | TYK2UGT1A1KCNH2JAK2JAK1 | |
| SCHEMBL20985242 | 0.75 | TYK2 (0.62) | TYK2UGT1A1KCNH2JAK2JAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111315737-B | Heteroaryl compounds substituted with sulfone pyridinylalkylamides | 百时美施贵宝公司 | 2024-06-18 | — | — | CN | disclosed |