Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | TYK2 | P29597 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | SYK | P43405 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20985220 | 1.00 | GRM5 (0.41) | GRM5L3MBTL1TYK2ALDH1A1HPGD | |
| SCHEMBL30940521 | 0.88 | GRM5 (0.43) | GRM5L3MBTL1TYK2ALDH1A1HPGD | |
| SCHEMBL20985236 | 0.88 | GRM5 (0.43) | GRM5L3MBTL1TYK2ALDH1A1HPGD | |
| SCHEMBL20985300 | 0.85 | GRM5 (0.45) | GRM5L3MBTL1ALDH1A1HPGDRAB9A | |
| SCHEMBL30940519 | 0.85 | GRM5 (0.45) | GRM5L3MBTL1ALDH1A1HPGDRAB9A | |
| SCHEMBL20985261 | 0.85 | TYK2 (0.43) | GRM5L3MBTL1TYK2 | |
| SCHEMBL30940484 | 0.84 | SYK (0.51) | GRM5L3MBTL1TYK2ALDH1A1HPGD | |
| SCHEMBL20985324 | 0.84 | SYK (0.51) | GRM5L3MBTL1TYK2ALDH1A1HPGD | |
| SCHEMBL20985312 | 0.78 | TYK2 (0.49) | GRM5TYK2PDE4D | |
| SCHEMBL30940488 | 0.78 | TYK2 (0.49) | GRM5TYK2PDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111315737-B | Heteroaryl compounds substituted with sulfone pyridinylalkylamides | 百时美施贵宝公司 | 2024-06-18 | — | — | CN | disclosed |