Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 20/20 | 0.60 |
| ▸ | JAK1 | P23458 | 5/20 | 0.53 |
| ▸ | JAK2 | O60674 | 3/20 | 0.53 |
| ▸ | JAK3 | P52333 | 1/20 | 0.53 |
| ▸ | STAT3 | P40763 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
| ▸ | KIT | P10721 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20985259 | 1.00 | TYK2 (0.60) | TYK2JAK1JAK2JAK3STAT3 | |
| SCHEMBL20985320 | 0.94 | TYK2 (0.62) | TYK2JAK1JAK2JAK3STAT3 | |
| SCHEMBL30617349 | 0.94 | TYK2 (0.62) | TYK2JAK1JAK2JAK3STAT3 | |
| SCHEMBL20985328 | 0.84 | TYK2 (0.46) | TYK2JAK1JAK2JAK3 | |
| SCHEMBL30940508 | 0.84 | TYK2 (0.46) | TYK2JAK1JAK2JAK3 | |
| SCHEMBL20985238 | 0.82 | TYK2 (0.61) | TYK2JAK1JAK2JAK3KCNH2 | |
| SCHEMBL30940531 | 0.82 | TYK2 (0.61) | TYK2JAK1JAK2JAK3KCNH2 | |
| SCHEMBL30617350 | 0.81 | TYK2 (0.62) | TYK2JAK1JAK2JAK3STAT3 | |
| SCHEMBL30617395 | 0.80 | TYK2 (0.61) | TYK2JAK1JAK2JAK3STAT3 | |
| SCHEMBL30617394 | 0.80 | TYK2 (0.56) | TYK2JAK1JAK2JAK3STAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111315737-B | Heteroaryl compounds substituted with sulfone pyridinylalkylamides | 百时美施贵宝公司 | 2024-06-18 | — | — | CN | disclosed |