Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 20/20 | 0.46 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | JAK1 | P23458 | 1/20 | 0.39 |
| ▸ | JAK3 | P52333 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20985328 | 1.00 | TYK2 (0.46) | TYK2JAK2JAK1JAK3 | |
| SCHEMBL20985235 | 0.94 | TYK2 (0.50) | TYK2JAK2JAK1JAK3 | |
| SCHEMBL21001866 | 0.90 | GRM5 (0.38) | TYK2 | |
| SCHEMBL20985259 | 0.84 | TYK2 (0.60) | TYK2JAK2JAK1JAK3 | |
| SCHEMBL30940503 | 0.84 | TYK2 (0.60) | TYK2JAK2JAK1JAK3 | |
| SCHEMBL30940514 | 0.82 | TYK2 (0.53) | TYK2 | |
| SCHEMBL20985291 | 0.82 | TYK2 (0.53) | TYK2 | |
| SCHEMBL30940521 | 0.79 | GRM5 (0.43) | TYK2JAK2JAK1 | |
| SCHEMBL20985236 | 0.79 | GRM5 (0.43) | TYK2JAK2JAK1 | |
| SCHEMBL20985320 | 0.78 | TYK2 (0.62) | TYK2JAK2JAK1JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111315737-B | Heteroaryl compounds substituted with sulfone pyridinylalkylamides | 百时美施贵宝公司 | 2024-06-18 | — | — | CN | disclosed |