SCHEMBL30940596

SCHEMBL30940596

COc1ccc(CCc2cc(OC)cc(O)c2O)cc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CALM1 P0DP23 3/20 0.63
NFKB1 P19838 1/20 0.56
NFKB2 Q00653 1/20 0.56
RELA Q04206 1/20 0.56
IGF1R P08069 1/20 0.53
ALOX15 P16050 1/20 0.53
ESR1 P03372 1/20 0.53
CYP19A1 P11511 1/20 0.53
ESR2 Q92731 1/20 0.53
SLC5A1 P13866 1/20 0.51
SLC5A2 P31639 1/20 0.51
AKR1B1 P15121 1/20 0.50
TAAR1 Q96RJ0 1/20 0.50
TDP1 Q9NUW8 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
PTPN1 P18031 1/20 0.48
NOS2 P35228 1/20 0.48
TUBB4A P04350 1/20 0.47
TUBB P07437 1/20 0.47
TUBA3C P0DPH7 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29350108 0.89 TDP1 (0.61) CALM1AKR1B1TDP1L3MBTL1ABCB1
SCHEMBL26134675 0.89 TDP1 (0.61) CALM1AKR1B1TDP1L3MBTL1ABCB1
SCHEMBL227115 0.83 ESR1 (0.73) CALM1NFKB1NFKB2RELAIGF1R
SCHEMBL29492427 0.80 ESR1 (0.69) CALM1NFKB1NFKB2RELAIGF1R
SCHEMBL1847390 0.80 ESR1 (0.69) CALM1NFKB1NFKB2RELAIGF1R
SCHEMBL4736569 0.78 ESR1 (0.82) CALM1NFKB1NFKB2RELAIGF1R
SCHEMBL17263517 0.78 AKR1B1 (0.68) CALM1NFKB1IGF1RALOX15AKR1B1
SCHEMBL3414787 0.78 CALM1 (0.84) CALM1NFKB1NFKB2RELAIGF1R
SCHEMBL27254011 0.77 CALM1 (1.00) CALM1NFKB1NFKB2RELAIGF1R
SCHEMBL30514717 0.77 CALM1 (0.86) CALM1NFKB1NFKB2RELAIGF1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118178365-A Application of dendrobinol and composition thereof in preparation of medicines or functional foods for preventing and/or treating digestive tract inflammation 合肥师范学院 2024-06-14 CN disclosed