Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.36 |
| ▸ | WDR5 | P61964 | 5/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 4/20 | 0.33 |
| ▸ | FGFR2 | P21802 | 4/20 | 0.33 |
| ▸ | FGFR3 | P22607 | 4/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.33 |
| ▸ | TIPARP | Q7Z3E1 | 4/20 | 0.32 |
| ▸ | ACVR1 | Q04771 | 3/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24967969 | 1.00 | GPR119 (0.36) | GPR119WDR5RIPK1FGFR2FGFR3 | |
| SCHEMBL24968389 | 0.91 | TIPARP (0.40) | GPR119WDR5RIPK1FGFR2FGFR3 | |
| SCHEMBL24968397 | 0.91 | TIPARP (0.40) | GPR119WDR5RIPK1FGFR2FGFR3 | |
| SCHEMBL24968352 | 0.91 | TIPARP (0.40) | GPR119WDR5RIPK1FGFR2FGFR3 | |
| SCHEMBL24968357 | 0.91 | GPR119 (0.37) | GPR119WDR5RIPK1FGFR2FGFR3 | |
| SCHEMBL24968240 | 0.86 | ACACB (0.35) | GPR119WDR5TIPARPKCNH2 | |
| SCHEMBL24968241 | 0.86 | ACACB (0.35) | GPR119WDR5TIPARPKCNH2 | |
| SCHEMBL24968457 | 0.86 | ACACB (0.35) | GPR119WDR5TIPARPKCNH2 | |
| SCHEMBL24967955 | 0.85 | TIPARP (0.42) | GPR119TIPARPKCNH2 | |
| SCHEMBL24968931 | 0.85 | GPR119 (0.37) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4378938-A1 | NOVEL PARP7 INHIBITOR AND USE THEREOF | Shanghai Qilu Pharmaceutical Research and Development Centre Ltd. (CN) | 2024-06-05 | — | — | EP | disclosed |