Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM1 | Q13255 | 11/20 | 0.54 |
| ▸ | GRM5 | P41594 | 11/20 | 0.54 |
| ▸ | WNT3A | P56704 | 1/20 | 0.51 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.48 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.46 |
| ▸ | KIT | P10721 | 1/20 | 0.46 |
| ▸ | NAMPT | P43490 | 1/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.45 |
| ▸ | HTR6 | P50406 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24968395 | 1.00 | GRM1 (0.54) | GRM1GRM5WNT3APDK4SCN9A | |
| SCHEMBL20266499 | 0.86 | GRM1 (0.64) | GRM1GRM5WNT3APDK4KIT | |
| SCHEMBL903903 | 0.85 | GRM1 (0.56) | GRM1GRM5WNT3APDK4NAMPT | |
| SCHEMBL24962318 | 0.85 | GRM1 (0.52) | GRM1GRM5PDK4KITNAMPT | |
| SCHEMBL976835 | 0.84 | GRM1 (0.55) | GRM1GRM5WNT3APDK4NAMPT | |
| SCHEMBL29746802 | 0.84 | GRM1 (0.55) | GRM1GRM5WNT3APDK4NAMPT | |
| SCHEMBL29907164 | 0.84 | GRM1 (0.55) | GRM1GRM5WNT3APDK4NAMPT | |
| SCHEMBL31039781 | 0.84 | GRM1 (0.55) | GRM1GRM5WNT3APDK4NAMPT | |
| SCHEMBL13096687 | 0.84 | GRM1 (0.55) | GRM1GRM5WNT3APDK4NAMPT | |
| SCHEMBL30198712 | 0.84 | GRM1 (0.55) | GRM1GRM5WNT3APDK4NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4378938-A1 | NOVEL PARP7 INHIBITOR AND USE THEREOF | Shanghai Qilu Pharmaceutical Research and Development Centre Ltd. (CN) | 2024-06-05 | — | — | EP | disclosed |